Lab and batch series machines for web processing (intermittent)


With its compact, clear and flexible design, the PML lab machine is ideally suitable for research and development as well as for the production of stability patterns and clinical patterns. The PML can be used both to process and package transdermal TTS/TDS therapeutic systems as well as for Oral Dissolvable Films (ODF).

  • Basic processes identical to those in the high performance production line
  • Operator friendly, flexible and adjustable
  • Easy and fast production of minimal quantities, stability patterns and clinical samples
  • Development of suitable production processes from the lab equipment to the high performance production line
  • Open design allows processes and options to be supplemented/modified later
  • Video

    Material with a web width of up to 100 mm can be processed on the PML.

  • PML -Production and packaging of TTS/TDS and ODF

    PML -Production and packaging of TTS/TDS and ODF.

  • PML – Gentle handling of sensitive oral film strips

    When producing ODF, the thin, sensitive material poses challenging demands on handling and web tension.

  • PML - Processing substrate

    Processing substrate in the production of TTS/TDS patches.


  • PML - Delivering ODF on bag material

    Delivering the oral dissolvable films (ODF) on the bag material.

  • PML - flexibly configurable for batch series

    Depending on the requirements, the compact PML can be flexibly expanded with additional modules.

  • PML - Contour cutting of TTS/TDS products

    Contour cutting with subsequent pulling off and winding up the punched waste.

  • PML - Drawing into bag web

    Drawing the product into the bag web. This is followed by punching the contour.

Technical data
  • Output: 40 products/min.
  • Web width: max. 100 mm
Final products
  • ODF – Oral Dissolvable Film
  • TDS – Matrix patch standard/ special design
  • TDS – Reservoir patch
  • TTS – Transdermal therapeutic systems
  • Packaging machines

Machine features

Web handling

Perfect web handling: Technical highly sensible components regulate feeding, transport and ejection of materials within the machine. Dancers, web edge controls, and winding and rewinding devices are the basic technologies for producing items such as patches.


The punching processes in a web processing system require the highest degree of precision and quality of raw materials in order to achieve the high outputs required during continuous operation, while also guaranteed the necessary accuracy. To achieve this, we use solid punching tools and die punching, in our machines.


Sealing is one of the central processes when connecting several product layers. We apply several technologies for this process. Depending on the material characteristics, we use such applications as platen sealing, roller sealing (hot and cold), pulse sealing, ultrasonic sealing or thermal sealing.

Camera inspection

Position and location accuracy, products in the sealing area, color deviations, damage or soiling to the detection of particles using sensor technology: Powerful camera systems are essential in quality inspection.


High-performance production of a
special capsule solution

With the Accordion Pill®, Intec Pharma has developed an innovative capsule platform that provides continuous drug release. The manufacturing technology for the product was supplied by Harro Höfliger.

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