Technologies and know-how
Dosing and filling
Reproducible precision for every product and medium
Whether manual in the laboratory, semi-automatic for small batches or fully automated for high performance: dosing and filling processes from Harro Höfliger ensure repeatable, precise results throughout the entire life cycle of your product. Our technologies cover all media – powders, liquids, lyo beads or solid materials – with dosing from micro to macro and with partial quantities or complete filling of the devices. Precise control and monitoring of the dosing process ensures that quality standards are consistently met – crucial for market approval and the success of your product.
Our expertise
Liquid dosing of vaccines in tubes, with subsequent sealing of the products under aseptic conditions.
Dosing of pellets on the rotary feeder of a capsule filling machine in containment design.
Powder dosing in blister strips for inhalers using a roller filler. This process is suitable for partial filling of cavities with a filling level of less than 50 %.
Precise dosing of powders containing active ingredients into reservoirs with several screw feeders on an assembly line for dry powder inhalers.
Liquid filling of diagnostic products under aseptic conditions.
Filling the powder chambers using a screw feeder on a dosing and assembly line for dry powder inhalers (DPIs).
Liquid filling of IV bags in a sterile environment.
Filling station on a high-performance capsule filling machine, dosing pellets. The patented trolley system enables the processes for powder, pellets, tablets and mini tablets to be changed quickly.
Rotary capsule filling machine in containment design for processing substances up to OEB 5; with integrated 100 % weighing.
Perfectly coordinated system solutions
In focus: Your product
No matter if you’re dealing with dry powder for inhalers, various filling materials in capsules, reagents for diagnostics, liquids for portion packs, or sterile preparations for infusions: Your product defines the process. In addition to technologies for dosing and filling, we also integrate coordinated control systems for consistent product quality. For example, an AMV sensor for determining the mass of powders and other solid formulations can be used independently of the dosing system and can safely detect the product at full machine speed.
Capsules
Hard capsules are among the most versatile pharmaceutical forms. We bring our process expertise to bear for precise filling. We offer machines from development to production, along with dosing methods for various solid and liquid media.
Projects and innovations with Harro Höfliger
Successful projects
Medical Technologies
Gentle handling of lyo bead pellets
For the handling of lyophilisates, Harro Höfliger offers a unique automated solution – the Lyo Bead Dispenser. The freeze-dried pellets are safely conveyed and accurately dosed via air flow.
Pharmaceutical Technologies
High-performance production of a special capsule solution
With the Accordion Pill®, Intec Pharma has developed an innovative capsule platform that provides continuous drug release. The manufacturing technology for the product was supplied by Harro Höfliger.
Pharmaceutical Technologies
Sterile filling of infusion bags
New B Innovation Limited (New β Innovation) uses a partially automated aseptic filling and sealing line for pre-sterilized infusion bags.
Pharmaceutical Technologies
Re-usable Inhaler Respimat®
Since 2004, the Respimat® has been ensuring easy inhalation for patients with diseases such as asthma and COPD. In 2019, Boehringer Ingelheim launched the re-usable version of this inhaler.